Compound Guides & Wellness Research — VanguardBIO
VanguardBIO / Research
Compound Guides
Science-backed research on peptides, recovery, cognition, and performance — written for people who demand evidence, not marketing.
18 articles
NAD+: Why Your Cellular Energy Is Collapsing
NAD+ levels drop 50% between 40 and 60. This single decline drives mitochondrial dysfunction, cognitive decline, and metabolic deterioration. Here is the science — and what actually works.
Melanotan II: Photoprotection, Metabolism, and Longevity
Melanotan II does two things most longevity compounds do not: it protects your DNA from UV damage and resets your metabolic rate. Here is the science behind both mechanisms.
HGH and Longevity: Restoration vs. Enhancement
Growth hormone declines 14% per decade after 30. The result is not just body composition changes — it is impaired cellular repair, worse sleep, and accelerated aging. Here is what low-dose restoration actually does.
Oxidative Stress: The Silent Driver of Biological Aging
Free radicals are not a wellness buzzword. They are the molecular mechanism behind cellular aging — and your antioxidant defenses are losing ground every year. Here is what that actually means.
The 8 Biomarkers That Actually Measure Biological Aging
Your chronological age is irrelevant. Your biological age — measured by specific, trackable markers — determines how you feel and how long you function well. Here is what to test and why.
Sirtuins: The Longevity Genes That Run on NAD+
Sirtuins are the proteins that regulate cellular aging, DNA repair, and metabolic health. They require NAD+ to function — and when NAD+ declines, so does everything they govern.
Why Peptides Are the Future of Anti-Aging Medicine
Peptides are not a trend. They are the signaling molecules your body already uses to regulate repair, growth, and cellular maintenance — and their therapeutic potential is only beginning to be understood.
TB-500 and Fibrosis: The Longevity Angle Nobody Talks About
TB-500 is known for tissue repair. Its longevity application is more fundamental: it actively counteracts fibrosis — the replacement of functional tissue with scar tissue that defines aging organs.
GHK-Cu: The Copper Peptide Rewriting Aging Biology
GHK-Cu regulates over 4,000 human genes. It rebuilds collagen, resets aged cells, and declines 300% between your 20s and 60s. Here is the science behind the most underrated longevity compound.
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